P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
401 L 14 5 19 0.270 0.437 View mutations
402 L 15 4 19 0.259 0.408 View mutations
403 G 19 0 19 0.001 0.552 View mutations
404 T 11 8 19 0.433 0.449 View mutations
405 L 10 9 19 0.477 0.425 View mutations
406 V 19 0 19 0.000 0.368 View mutations
407 Q 19 0 19 0.000 0.464 View mutations
408 L 5 14 19 0.648 0.502 View mutations
409 L 19 0 19 0.000 0.475 View mutations
410 G 19 0 19 0.003 0.386 View mutations
411 S 7 12 19 0.699 0.507 View mutations
412 D 6 13 19 0.702 0.444 View mutations
413 D 0 19 19 0.962 0.564 View mutations
414 I 16 3 19 0.165 0.386 View mutations
415 N 19 0 19 0.015 0.461 View mutations
416 V 2 17 19 0.893 0.462 View mutations
417 V 12 7 19 0.399 0.478 View mutations
418 T 18 1 19 0.039 0.378 View mutations
419 C 11 8 19 0.415 0.482 View mutations
420 A 1 18 19 0.942 0.519 View mutations
421 A 19 0 19 0.032 0.393 View mutations
422 G 17 2 19 0.095 0.335 View mutations
423 I 2 17 19 0.896 0.629 View mutations
424 L 0 19 19 0.998 0.717 View mutations
425 S 10 9 19 0.444 0.485 View mutations