P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
426 N 5 14 19 0.744 0.656 View mutations
427 L 0 19 19 1.000 0.747 View mutations
428 T 0 19 19 1.000 0.776 View mutations
429 C 0 19 19 0.982 0.661 View mutations
430 N 4 15 19 0.810 0.593 View mutations
431 N 3 16 19 0.823 0.568 View mutations
432 Y 18 1 19 0.119 0.471 View mutations
433 K 19 0 19 0.020 0.450 View mutations
434 N 0 19 19 0.997 0.548 View mutations
435 K 5 14 19 0.713 0.568 View mutations
436 M 19 0 19 0.023 0.470 View mutations
437 M 17 2 19 0.103 0.461 View mutations
438 V 1 18 19 0.934 0.531 View mutations
439 C 16 3 19 0.165 0.490 View mutations
440 Q 2 17 19 0.879 0.458 View mutations
441 V 15 4 19 0.275 0.416 View mutations
442 G 18 1 19 0.053 0.449 View mutations
443 G 19 0 19 0.039 0.341 View mutations
444 I 4 15 19 0.790 0.564 View mutations
445 E 18 1 19 0.055 0.417 View mutations
446 A 19 0 19 0.004 0.464 View mutations
447 L 12 7 19 0.378 0.475 View mutations
448 V 19 0 19 0.002 0.437 View mutations
449 R 16 3 19 0.153 0.429 View mutations
450 T 18 1 19 0.103 0.469 View mutations