P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
451 V 17 2 19 0.153 0.456 View mutations
452 L 16 3 19 0.179 0.404 View mutations
453 R 19 0 19 0.013 0.420 View mutations
454 A 19 0 19 0.000 0.419 View mutations
455 G 17 2 19 0.097 0.462 View mutations
456 D 12 7 19 0.361 0.486 View mutations
457 R 11 8 19 0.436 0.494 View mutations
458 E 0 19 19 0.980 0.652 View mutations
459 D 15 4 19 0.219 0.391 View mutations
460 I 19 0 19 0.008 0.373 View mutations
461 T 15 4 19 0.221 0.453 View mutations
462 E 0 19 19 1.000 0.822 View mutations
463 P 0 19 19 0.998 0.787 View mutations
464 A 17 2 19 0.099 0.396 View mutations
465 I 2 17 19 0.896 0.670 View mutations
466 C 0 19 19 1.000 0.830 View mutations
467 A 0 19 19 0.996 0.840 View mutations
468 L 1 18 19 0.947 0.728 View mutations
469 R 0 19 19 1.000 0.837 View mutations
470 H 0 19 19 1.000 0.798 View mutations
471 L 0 19 19 1.000 0.804 View mutations
472 T 12 7 19 0.436 0.427 View mutations
473 S 17 2 19 0.127 0.409 View mutations
474 R 19 0 19 0.005 0.365 View mutations
475 H 2 17 19 0.903 0.557 View mutations