P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
476 Q 19 0 19 0.013 0.443 View mutations
477 E 8 11 19 0.518 0.437 View mutations
478 A 19 0 19 0.045 0.430 View mutations
479 E 2 17 19 0.901 0.590 View mutations
480 M 13 6 19 0.323 0.438 View mutations
481 A 0 19 19 0.999 0.596 View mutations
482 Q 0 19 19 0.993 0.633 View mutations
483 N 11 8 19 0.398 0.498 View mutations
484 A 15 4 19 0.192 0.440 View mutations
485 V 7 12 19 0.625 0.529 View mutations
486 R 0 19 19 1.000 0.600 View mutations
487 L 13 6 19 0.268 0.439 View mutations
488 H 19 0 19 0.011 0.417 View mutations
489 Y 19 0 19 0.009 0.366 View mutations
490 G 19 0 19 0.021 0.394 View mutations
491 L 5 14 19 0.730 0.526 View mutations
492 P 3 16 19 0.799 0.467 View mutations
493 V 14 5 19 0.266 0.405 View mutations
494 V 19 0 19 0.002 0.473 View mutations
495 V 8 11 19 0.592 0.501 View mutations
496 K 19 0 19 0.013 0.374 View mutations
497 L 8 11 19 0.636 0.512 View mutations
498 L 0 19 19 0.991 0.535 View mutations
499 H 17 2 19 0.129 0.470 View mutations
500 P 15 4 19 0.266 0.418 View mutations