P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
501 P 15 4 19 0.216 0.484 View mutations
502 S 2 17 19 0.884 0.465 View mutations
503 H 2 17 19 0.906 0.512 View mutations
504 W 0 19 19 1.000 0.550 View mutations
505 P 0 19 19 1.000 0.692 View mutations
506 L 0 19 19 0.993 0.554 View mutations
507 I 4 15 19 0.801 0.523 View mutations
508 K 0 19 19 1.000 0.728 View mutations
509 A 8 11 19 0.659 0.534 View mutations
510 T 7 12 19 0.619 0.512 View mutations
511 V 1 18 19 0.948 0.626 View mutations
512 G 4 15 19 0.819 0.632 View mutations
513 L 18 1 19 0.075 0.315 View mutations
514 I 1 18 19 0.971 0.612 View mutations
515 R 0 19 19 1.000 0.683 View mutations
516 N 4 15 19 0.771 0.641 View mutations
517 L 6 13 19 0.705 0.567 View mutations
518 A 0 19 19 0.985 0.687 View mutations
519 L 0 19 19 1.000 0.589 View mutations
520 C 2 17 19 0.894 0.572 View mutations
521 P 17 2 19 0.126 0.410 View mutations
522 A 6 13 19 0.697 0.450 View mutations
523 N 0 19 19 1.000 0.544 View mutations
524 H 18 1 19 0.074 0.362 View mutations
525 A 19 0 19 0.001 0.403 View mutations