P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
526 P 5 14 19 0.716 0.508 View mutations
527 L 19 0 19 0.022 0.488 View mutations
528 R 18 1 19 0.050 0.454 View mutations
529 E 19 0 19 0.001 0.485 View mutations
530 Q 5 14 19 0.700 0.419 View mutations
531 G 6 13 19 0.696 0.432 View mutations
532 A 4 15 19 0.778 0.452 View mutations
533 I 6 13 19 0.614 0.508 View mutations
534 P 6 13 19 0.691 0.436 View mutations
535 R 2 17 19 0.775 0.434 View mutations
536 L 4 15 19 0.741 0.508 View mutations
537 V 18 1 19 0.060 0.386 View mutations
538 Q 9 10 19 0.512 0.438 View mutations
539 L 19 0 19 0.082 0.380 View mutations
540 L 17 2 19 0.123 0.445 View mutations
541 V 19 0 19 0.064 0.428 View mutations
542 R 1 18 19 0.928 0.477 View mutations
543 A 19 0 19 0.008 0.452 View mutations
544 H 8 11 19 0.536 0.500 View mutations
545 Q 19 0 19 0.035 0.477 View mutations
546 D 6 13 19 0.682 0.507 View mutations
547 T 18 1 19 0.057 0.422 View mutations
548 Q 19 0 19 0.000 0.533 View mutations
549 R 19 0 19 0.001 0.624 View mutations
550 R 18 1 19 0.065 0.635 View mutations