P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
551 T 16 3 19 0.212 0.650 View mutations
552 S 14 5 19 0.286 0.609 View mutations
553 M 13 6 19 0.349 0.600 View mutations
554 G 8 11 19 0.531 0.426 View mutations
555 G 14 5 19 0.238 0.630 View mutations
556 T 18 1 19 0.073 0.787 View mutations
557 Q 18 1 19 0.046 0.711 View mutations
558 Q 19 0 19 0.012 0.724 View mutations
559 Q 19 0 19 0.079 0.686 View mutations
560 F 19 0 19 0.021 0.576 View mutations
561 V 19 0 19 0.001 0.615 View mutations
562 E 9 10 19 0.608 0.434 View mutations
563 G 0 19 19 1.000 0.550 View mutations
564 V 1 18 19 0.947 0.549 View mutations
565 R 1 18 19 0.951 0.519 View mutations
566 M 3 16 19 0.825 0.541 View mutations
567 E 1 18 19 0.952 0.565 View mutations
568 E 1 18 19 0.943 0.583 View mutations
569 I 4 15 19 0.802 0.509 View mutations
570 V 18 1 19 0.055 0.406 View mutations
571 E 1 18 19 0.950 0.538 View mutations
572 G 0 19 19 0.999 0.454 View mutations
573 C 3 16 19 0.867 0.442 View mutations
574 T 9 10 19 0.508 0.429 View mutations
575 G 0 19 19 0.994 0.570 View mutations