P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
576 A 0 19 19 0.974 0.543 View mutations
577 L 4 15 19 0.781 0.520 View mutations
578 H 4 15 19 0.739 0.532 View mutations
579 I 17 2 19 0.105 0.465 View mutations
580 L 5 14 19 0.769 0.511 View mutations
581 A 14 5 19 0.235 0.472 View mutations
582 R 7 12 19 0.626 0.507 View mutations
583 D 19 0 19 0.000 0.383 View mutations
584 V 19 0 19 0.013 0.496 View mutations
585 H 19 0 19 0.004 0.515 View mutations
586 N 19 0 19 0.002 0.428 View mutations
587 R 6 13 19 0.708 0.503 View mutations
588 I 19 0 19 0.013 0.514 View mutations
589 V 8 11 19 0.496 0.433 View mutations
590 I 3 16 19 0.830 0.443 View mutations
591 R 11 8 19 0.419 0.427 View mutations
592 G 16 3 19 0.227 0.490 View mutations
593 L 19 0 19 0.000 0.528 View mutations
594 N 14 5 19 0.253 0.498 View mutations
595 T 7 12 19 0.643 0.424 View mutations
596 I 1 18 19 0.941 0.502 View mutations
597 P 0 19 19 0.988 0.493 View mutations
598 L 2 17 19 0.894 0.479 View mutations
599 F 0 19 19 0.957 0.473 View mutations
600 V 1 18 19 0.937 0.606 View mutations