P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
601 Q 2 17 19 0.854 0.518 View mutations
602 L 2 17 19 0.839 0.601 View mutations
603 L 0 19 19 0.997 0.557 View mutations
604 Y 1 18 19 0.919 0.554 View mutations
605 S 3 16 19 0.880 0.508 View mutations
606 P 7 12 19 0.645 0.444 View mutations
607 I 11 8 19 0.424 0.498 View mutations
608 E 15 4 19 0.283 0.440 View mutations
609 N 19 0 19 0.016 0.384 View mutations
610 I 4 15 19 0.757 0.508 View mutations
611 Q 2 17 19 0.896 0.531 View mutations
612 R 19 0 19 0.004 0.320 View mutations
613 V 18 1 19 0.042 0.358 View mutations
614 A 1 18 19 0.947 0.546 View mutations
615 A 7 12 19 0.630 0.540 View mutations
616 G 7 12 19 0.594 0.546 View mutations
617 V 1 18 19 0.914 0.576 View mutations
618 L 0 19 19 1.000 0.619 View mutations
619 C 9 10 19 0.500 0.505 View mutations
620 E 0 19 19 0.933 0.656 View mutations
621 L 0 19 19 1.000 0.575 View mutations
622 A 5 14 19 0.787 0.565 View mutations
623 Q 18 1 19 0.063 0.466 View mutations
624 D 2 17 19 0.860 0.530 View mutations
625 K 0 19 19 0.999 0.519 View mutations