P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
626 E 5 14 19 0.734 0.430 View mutations
627 A 12 7 19 0.343 0.434 View mutations
628 A 4 15 19 0.796 0.576 View mutations
629 E 13 6 19 0.283 0.406 View mutations
630 A 18 1 19 0.064 0.424 View mutations
631 I 0 19 19 0.999 0.590 View mutations
632 E 1 18 19 0.947 0.616 View mutations
633 A 18 1 19 0.056 0.473 View mutations
634 E 1 18 19 0.938 0.553 View mutations
635 G 0 19 19 0.995 0.591 View mutations
636 A 0 19 19 1.000 0.598 View mutations
637 T 2 17 19 0.879 0.567 View mutations
638 A 5 14 19 0.640 0.513 View mutations
639 P 0 19 19 1.000 0.652 View mutations
640 L 0 19 19 1.000 0.639 View mutations
641 T 15 4 19 0.287 0.417 View mutations
642 E 13 6 19 0.317 0.458 View mutations
643 L 0 19 19 0.988 0.650 View mutations
644 L 0 19 19 0.975 0.661 View mutations
645 H 5 14 19 0.654 0.540 View mutations
646 S 5 14 19 0.687 0.564 View mutations
647 R 5 14 19 0.654 0.502 View mutations
648 N 0 19 19 1.000 0.648 View mutations
649 E 0 19 19 0.986 0.697 View mutations
650 G 0 19 19 0.995 0.648 View mutations