P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
651 V 1 18 19 0.939 0.569 View mutations
652 A 3 16 19 0.828 0.610 View mutations
653 T 3 16 19 0.794 0.598 View mutations
654 Y 6 13 19 0.580 0.567 View mutations
655 A 11 8 19 0.412 0.481 View mutations
656 A 3 16 19 0.853 0.632 View mutations
657 A 0 19 19 0.973 0.693 View mutations
658 V 6 13 19 0.685 0.530 View mutations
659 L 8 11 19 0.575 0.520 View mutations
660 F 2 17 19 0.896 0.642 View mutations
661 R 0 19 19 1.000 0.662 View mutations
662 M 8 11 19 0.541 0.520 View mutations
663 S 14 5 19 0.319 0.429 View mutations
664 E 9 10 19 0.484 0.508 View mutations
665 D 2 17 19 0.885 0.628 View mutations
666 K 1 18 19 0.915 0.574 View mutations
667 P 14 5 19 0.276 0.497 View mutations
668 Q 19 0 19 0.102 0.430 View mutations
669 D 3 16 19 0.818 0.551 View mutations
670 Y 18 1 19 0.048 0.406 View mutations
671 K 19 0 19 0.095 0.445 View mutations
672 K 0 19 19 0.999 0.597 View mutations
673 R 1 18 19 0.944 0.639 View mutations
674 L 5 14 19 0.689 0.571 View mutations
675 S 2 17 19 0.890 0.530 View mutations