P35222 (CTNNB1)

Overview
Predicted structure (AF):
AF-P35222-F1-model_v4
Uniprot entry:
P35222
Gene:
CTNNB1
Protein length:
781 residues
Mutations found:
14838
Benign based on D2Deep prediction:
8232 out of 14838 mutations
Pathogenic based on D2Deep prediction:
6606 out of 14838 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 14838 mutations across 781 unique positions. There are 8232 benign and 6606 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 R 2 17 19 0.811 0.727 View mutations
152 A 0 19 19 1.000 0.731 View mutations
153 I 7 12 19 0.671 0.568 View mutations
154 P 9 10 19 0.513 0.517 View mutations
155 E 0 19 19 1.000 0.762 View mutations
156 L 6 13 19 0.686 0.577 View mutations
157 T 14 5 19 0.287 0.407 View mutations
158 K 1 18 19 0.954 0.672 View mutations
159 L 1 18 19 0.939 0.797 View mutations
160 L 1 18 19 0.919 0.707 View mutations
161 N 5 14 19 0.718 0.600 View mutations
162 D 0 19 19 1.000 0.747 View mutations
163 E 2 17 19 0.892 0.675 View mutations
164 D 0 19 19 1.000 0.710 View mutations
165 Q 15 4 19 0.256 0.453 View mutations
166 V 1 18 19 0.902 0.593 View mutations
167 V 5 14 19 0.716 0.561 View mutations
168 V 4 15 19 0.745 0.537 View mutations
169 N 18 1 19 0.056 0.368 View mutations
170 K 15 4 19 0.230 0.396 View mutations
171 A 0 19 19 0.996 0.566 View mutations
172 A 12 7 19 0.373 0.484 View mutations
173 V 19 0 19 0.033 0.451 View mutations
174 M 19 0 19 0.014 0.468 View mutations
175 V 7 12 19 0.597 0.536 View mutations