Q06643 (TNFC)

Overview
Predicted structure (AF):
AF-Q06643-F1-model_v4
Uniprot entry:
Q06643
Gene:
TNFC
Protein length:
244 residues
Mutations found:
4635
Benign based on D2Deep prediction:
3101 out of 4635 mutations
Pathogenic based on D2Deep prediction:
1534 out of 4635 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4635 mutations across 244 unique positions. There are 3101 benign and 1534 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
151 D 19 0 19 0.001 1.000 View mutations
152 P 19 0 19 0.024 0.900 View mutations
153 Q 19 0 19 0.001 0.916 View mutations
154 G 19 0 19 0.002 0.872 View mutations
155 R 19 0 19 0.057 0.823 View mutations
156 S 19 0 19 0.008 0.711 View mutations
157 V 19 0 19 0.001 0.460 View mutations
158 T 19 0 19 0.080 0.405 View mutations
159 L 16 3 19 0.212 0.439 View mutations
160 R 10 9 19 0.427 0.439 View mutations
161 S 15 4 19 0.360 0.453 View mutations
162 S 3 16 19 0.822 0.472 View mutations
163 L 3 16 19 0.844 0.625 View mutations
164 Y 9 10 19 0.502 0.430 View mutations
165 R 15 4 19 0.234 0.423 View mutations
166 A 16 3 19 0.181 0.418 View mutations
167 G 19 0 19 0.006 0.401 View mutations
168 G 19 0 19 0.027 0.431 View mutations
169 A 19 0 19 0.026 0.452 View mutations
170 Y 19 0 19 0.069 0.487 View mutations
171 G 13 6 19 0.364 0.398 View mutations
172 P 16 3 19 0.202 0.475 View mutations
173 G 19 0 19 0.020 0.396 View mutations
174 T 19 0 19 0.007 0.507 View mutations
175 P 19 0 19 0.056 0.490 View mutations