P10415 (BCL2)

Overview
Predicted structure (AF):
AF-P10415-F1-model_v4
Uniprot entry:
P10415
Gene:
BCL2
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
3113 out of 4540 mutations
Pathogenic based on D2Deep prediction:
1427 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4540 mutations across 239 unique positions. There are 3113 benign and 1427 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
76 A 18 1 19 0.051 0.905 View mutations
77 A 19 0 19 0.064 0.939 View mutations
78 P 17 2 19 0.151 0.870 View mutations
79 G 19 0 19 0.013 0.914 View mutations
80 A 19 0 19 0.065 0.870 View mutations
81 A 19 0 19 0.033 0.914 View mutations
82 A 19 0 19 0.006 0.873 View mutations
83 G 19 0 19 0.016 0.819 View mutations
84 P 19 0 19 0.010 0.786 View mutations
85 A 19 0 19 0.004 0.800 View mutations
86 L 19 0 19 0.001 0.701 View mutations
87 S 19 0 19 0.013 0.788 View mutations
88 P 19 0 19 0.018 0.632 View mutations
89 V 19 0 19 0.000 0.612 View mutations
90 P 19 0 19 0.000 0.473 View mutations
91 P 19 0 19 0.001 0.545 View mutations
92 V 19 0 19 0.000 0.390 View mutations
93 V 16 3 19 0.284 0.420 View mutations
94 H 18 1 19 0.099 0.374 View mutations
95 L 14 5 19 0.299 0.409 View mutations
96 T 8 11 19 0.625 0.520 View mutations
97 L 19 0 19 0.122 0.309 View mutations
98 R 19 0 19 0.014 0.400 View mutations
99 Q 12 7 19 0.396 0.479 View mutations
100 A 7 12 19 0.649 0.569 View mutations