P10415 (BCL2)

Overview
Predicted structure (AF):
AF-P10415-F1-model_v4
Uniprot entry:
P10415
Gene:
BCL2
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
3113 out of 4540 mutations
Pathogenic based on D2Deep prediction:
1427 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 4540 mutations across 239 unique positions. There are 3113 benign and 1427 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
126 A 0 19 19 0.939 0.714 View mutations
127 R 0 19 19 0.942 0.596 View mutations
128 G 5 14 19 0.664 0.507 View mutations
129 R 16 3 19 0.161 0.449 View mutations
130 F 0 19 19 0.955 0.687 View mutations
131 A 4 15 19 0.818 0.508 View mutations
132 T 5 14 19 0.723 0.508 View mutations
133 V 11 8 19 0.532 0.464 View mutations
134 V 4 15 19 0.804 0.606 View mutations
135 E 2 17 19 0.862 0.691 View mutations
136 E 3 16 19 0.873 0.682 View mutations
137 L 1 18 19 0.898 0.828 View mutations
138 F 1 18 19 0.798 0.825 View mutations
139 R 11 8 19 0.328 0.463 View mutations
140 D 15 4 19 0.254 0.259 View mutations
141 G 18 1 19 0.119 0.061 View mutations
142 V 19 0 19 0.001 0.021 View mutations
143 N 19 0 19 0.007 0.032 View mutations
144 W 19 0 19 0.131 0.108 View mutations
145 G 19 0 19 0.051 0.000 View mutations
146 R 18 1 19 0.085 0.074 View mutations
147 I 15 4 19 0.315 0.306 View mutations
148 V 19 0 19 0.040 0.183 View mutations
149 A 18 1 19 0.064 0.113 View mutations
150 F 15 4 19 0.184 0.292 View mutations