P10415 (BCL2)

Overview
Predicted structure (AF):
AF-P10415-F1-model_v4
Uniprot entry:
P10415
Gene:
BCL2
Protein length:
239 residues
Mutations found:
4540
Benign based on D2Deep prediction:
3113 out of 4540 mutations
Pathogenic based on D2Deep prediction:
1427 out of 4540 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

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Table results: 4540 mutations across 239 unique positions. There are 3113 benign and 1427 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
101 G 17 2 19 0.106 0.284 View mutations
102 D 19 0 19 0.004 0.312 View mutations
103 D 10 9 19 0.550 0.489 View mutations
104 F 0 19 19 0.965 0.726 View mutations
105 S 6 13 19 0.708 0.590 View mutations
106 R 18 1 19 0.140 0.444 View mutations
107 R 19 0 19 0.032 0.332 View mutations
108 Y 4 15 19 0.740 0.663 View mutations
109 R 16 3 19 0.153 0.426 View mutations
110 R 19 0 19 0.003 0.392 View mutations
111 D 10 9 19 0.432 0.485 View mutations
112 F 1 18 19 0.853 0.738 View mutations
113 A 18 1 19 0.053 0.439 View mutations
114 E 18 1 19 0.038 0.373 View mutations
115 M 2 17 19 0.855 0.711 View mutations
116 S 13 6 19 0.393 0.400 View mutations
117 S 11 8 19 0.541 0.479 View mutations
118 Q 18 1 19 0.089 0.324 View mutations
119 L 4 15 19 0.753 0.700 View mutations
120 H 6 13 19 0.684 0.599 View mutations
121 L 1 18 19 0.918 0.801 View mutations
122 T 8 11 19 0.611 0.540 View mutations
123 P 0 19 19 0.997 0.776 View mutations
124 F 10 9 19 0.488 0.497 View mutations
125 T 1 18 19 0.926 0.583 View mutations