P06748 (NPM1)

Overview
Predicted structure (AF):
AF-P06748-F1-model_v4
Uniprot entry:
P06748
Gene:
NPM1
Protein length:
294 residues
Mutations found:
5585
Benign based on D2Deep prediction:
4154 out of 5585 mutations
Pathogenic based on D2Deep prediction:
1431 out of 5585 mutations
Scores that are greater than or equal to 0.5 are considered "Pathogenic", while scores that are less than 0.5 are considered "Benign".
Predicted structure
Mutation Scores
Long range effect of the mutations
Short range effect of the mutations

Positions

Download displayed results as CSV

Table results: 5585 mutations across 294 unique positions. There are 4154 benign and 1431 pathogenic mutations.

Position Original Benign Pathogenic Total D2Deep score mean Overall confidence mean Actions
176 D 19 0 19 0.007 0.953 View mutations
177 D 19 0 19 0.001 0.955 View mutations
178 D 19 0 19 0.000 0.911 View mutations
179 D 19 0 19 0.004 0.884 View mutations
180 D 19 0 19 0.006 0.859 View mutations
181 F 19 0 19 0.001 0.837 View mutations
182 D 19 0 19 0.000 0.820 View mutations
183 D 19 0 19 0.003 0.787 View mutations
184 E 19 0 19 0.002 0.766 View mutations
185 E 19 0 19 0.000 0.733 View mutations
186 A 19 0 19 0.000 0.692 View mutations
187 E 19 0 19 0.001 0.638 View mutations
188 E 19 0 19 0.001 0.617 View mutations
189 K 17 2 19 0.191 0.615 View mutations
190 A 19 0 19 0.001 0.591 View mutations
191 P 19 0 19 0.056 0.494 View mutations
192 V 19 0 19 0.005 0.516 View mutations
193 K 19 0 19 0.035 0.698 View mutations
194 K 19 0 19 0.030 0.719 View mutations
195 S 18 1 19 0.039 0.688 View mutations
196 I 19 0 19 0.001 0.723 View mutations
197 R 19 0 19 0.001 0.807 View mutations
198 D 19 0 19 0.041 0.760 View mutations
199 T 19 0 19 0.002 0.782 View mutations
200 P 17 2 19 0.130 0.664 View mutations